Risks of IV Phenergan

Receiving the antinausea drug Phenergan intravenously can have serious consequences if the drug infiltrates or extravasates into surrounding tissue. The manufacturer has warned that significant tissue or nerve damage can result. We have handled cases where the patient developed RSD (reflex sympathetic dystrophy) or CRPS (complex regional pain syndrome) as a result. Receiving the drug orally, through deep muscular injection, or in suppository form are generally safer alternatives.

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